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작성일 : 15-09-07 16:04
Eye tracking and gating system for proton therapy of orbital tumors
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Purpose: A new motion-based gated proton therapy for the treatment of orbital tumors using
real-time eye-tracking system was designed and evaluated.
Methods:We developed our system by image-pattern matching, using a normalized cross-correlation
technique with LabVIEW 8.6 and Vision Assistant 8.6 (National Instruments, Austin, TX). To
measure the pixel spacing of an image consistently, four different calibration modes such as the
point-detection, the edge-detection, the line-measurement, and the manual measurement mode were
suggested and used. After these methods were applied to proton therapy, gating was performed, and
radiation dose distributions were evaluated.
Results: Moving phantom verification measurements resulted in errors of less than 0.1 mm for given
ranges of translation. Dosimetric evaluation of the beam-gating system versus nongated treatment
delivery with a moving phantom shows that while there was only 0.83 mm growth in lateral penumbra
for gated radiotherapy, there was 4.95 mm growth in lateral penumbra in case of nongated exposure.
The analysis from clinical results suggests that the average of eye movements depends distinctively
on each patient by showing 0.44 mm, 0.45 mm, and 0.86 mm for three patients, respectively.
Conclusions: The developed automatic eye-tracking based beam-gating system enabled us to perform
high-precision proton radiotherapy of orbital tumors. ? 2012 American Association of Physicists in
Medicine.
 
 
 
Dongho Shin
Proton Therapy Center, National Cancer Center, Goyang, Gyeonggi 410-769, Republic of Korea
Seung Hoon Yoo
Department of Radiation Oncology, CHA Bundang Medical Center, CHA University,
Seongnam, Gyeonggi 463-712, Republic of Korea
Sung Ho Moon
Proton Therapy Center, National Cancer Center, Goyang, Gyeonggi 410-769, Republic of Korea
Myonggeun Yoon
Department of Radiological Science, Korea University, Seoul 136-703, Republic of Korea
Se Byeong Lee
Proton Therapy Center, National Cancer Center, Goyang, Gyeonggi 410-769, Republic of Korea
Sung Yong Parka)
Proton Therapy Center, McLaren Cancer Institute, Flint, Michigan 48532
 
Medical Physics, Vol. 39, No. 7, July 2012