This
study was designed to evaluate the effectiveness of a newly developed quality
assurance system for electromagnetic field therapy called tumor treating fields
therapy, which uses an alternating electric field to treat cancer based on an
intermediate frequency of 100–300 kHz. The quality assurance system for
electromagnetic field therapy consisted of a water phantom, a probe, and a
digital data acquisition (DAQ) board. Low intensity alternating electric fields
(200 kHz, 0–.1 V/cm) were created within the water phantom using a function
generator and a high voltage amplifier. The electric potential formed inside
the water phantom was measured using the probe and DAQ board. The electric
field intensity was derived by measuring the electric potential at the 190
points (19 × 10 cm2) of the midplane. Accuracy was evaluated by
gamma index analysis, which compared the measured electric field and the
simulation result. The mean difference between the simulation result and the
measured electric potentials within the water phantom was 0.31 V. The gamma
passing rate for the tolerance levels of 0.5 V/5 mm was 95.5% for electric
potential comparison showing good agreement between simulation and experimental
results. The mean difference between the electric field distribution within the
water phantom and the simulated values was 0.09 V/cm and the gamma passing rate
for the tolerance levels of (0.2 V/cm)/5 mm was ~ 97.3%. These results
confirmed the feasibility of the quality assurance system for electromagnetic
field therapy.
Heehun Sung, Jaehyeon Seo, Geon Oh, Yongha Gi, Hyunwoo Kim & Myonggeun Yoon
Department of Bioengineering, Korea
University, Seoul, Republic of Korea
Jong Hyun Kim & Myonggeun Yoon
FieldCure Ltd, Seoul, Republic of Korea
Yunhui Jo
Institute of Global Health Technology,
Korea University, Seoul, Republic of Korea
J.
Korean Phys. Soc. 81, 1029–1038 (2022).
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