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작성일 : 20-03-09 18:07
Feasibility study of a plastic scintillating plate-based treatment beam fluence monitoring system for use in pencil beam scanning proton therapy
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조회 : 2,917  

Purpose: The purpose of this study was to describe a plastic scintillating plate-based gantryattachable
dosimetry system for pencil beam scanning proton therapy to monitor entrance proton beam
fluence, and to evaluate the dosimetric characteristics of this system and its feasibility for clinical use.
Methods: The dosimetry system, consisting of a plastic scintillating plate and a CMOS camera, was
attached to a dedicated scanning nozzle and scintillation during proton beam irradiation was
recorded. Dose distribution was calculated from the accumulated recorded frames. The dosimetric
characteristics (energy dependency, dose linearity, dose rate dependency, and reproducibility) of the
gantry-attachable dosimetry system for use with therapeutic proton beams were measured, and the
feasibility of this system during clinical use was evaluated by determining selected quality assurance
items at our institution.
Results: The scintillating plate shortened the range of the proton beam by the water-equivalent thickness
of the plate and broadened the spatial profile of the single proton spot by 11% at 70 MeV. The
developed system functioned independently of the beam energy (<1.3%) and showed dose linearity,
and also functioned independently of the dose rate. The feasibility of the system for clinical use was
evaluated by comparing the measured quality assurance dose distribution to that of the treatment
planning system. The gamma passing rate with a criterion of 3%/3 mm was 97.58%.
Conclusions: This study evaluated the dosimetric characteristics of a plastic scintillating plate-based
dosimetry system for use with scanning proton beams. The ability to account for the interference of
the dosimetry system on the therapeutic beam enabled offline monitoring of the entrance beam fluence
of the pencil beam scanning proton therapy independent of the treatment system with high resolution
and in a cost-effective manner.

Seonghoon Jeong
Department of Bio-Convergence Engineering, Korea University, Seoul, Republic of Korea
Kwangzoo Chung, Sung Hwan Ahn, and Boram Lee
Department of Radiation Oncology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of
Korea
Jaehyeon Seo and Myonggeun Yoon
Department of Bio-Convergence Engineering, Korea University, Seoul, Republic of Korea

Med. Phys. 47 (2), February 2020.