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Study on the Dose Uncertainties in the Lung during Passive Proton Irradiation with a Proton Beam Range Compensator
 글쓴이 : 관리자
조회 : 2,643  

A moving phantom is manufactured for mimicking lung model to study the dose uncertainty from CT number-stopping power conversion and dose calculation in the soft tissue, light lung tissue and bone regions during passive proton irradiation with compensator smearing value. The phantom is scanned with a CT system, and a proton beam irradiation plan is carried out with the use of a treatment planning system (Eclipse). In the case of the moving phantom, a RPM system is used for respiratory gating. The uncertainties in the dose distribution between the measured data and the planned data are investigated by a gamma analysis with 3%-3 mm acceptance criteria. To investigate smearing effect, three smearing values (0.3 cm, 0.7 cm, 1.2 cm) are used to for fixed and moving phantom system. For both fixed and moving phantom, uncertainties in the light lung tissue are severe than those in soft tissue region in which the dose uncertainties are within clinically tolerable ranges. As the smearing value increases, the uncertainty in the proton dose distribution decreases.

Seung Hoon Yoo
Division of Heavy-Ion Clinical Research, Korea Institute of Radiological and Medical Science, Seoul 01812, Korea
Jae Man Son and Myonggeun Yoon
Department of Department of Bio-Convergence Engineering, Korea University, Seoul 02841, Korea
Sung Yong Park
McLaren Proton Therapy Center, McLaren Cancer Institute, Flint, Michigan 48532, USA
Dongho Shin
Proton Therapy Center, National Cancer Center, Goyang 10408, Korea
Byung Jun Min
Department of Radiation Oncology, Kangbuk Samsung Hospital,
Sungkyunkwan University School of Medicine, Seoul 03181, Korea

Journal of the Korean Physical Society, Vol. 72, No. 11, June 2018, pp. 1369∼1378